contentSlug

type

ContentSlug_ContentQuery

slug

ContentPageContentQuery

content

trendingContent

query ContentSlug_ContentQuery(
  $contentSlug: String!
  $type: [ContentType!]
) {
  ...ContentPageContentQuery_13QmVO
}

fragment CompanyDetails_Content on Content {
  __isContent: __typename
  companies {
    name
    description
    pageUrl
    id
  }
}

fragment ContentBasicInfo on Content {
  __isContent: __typename
  id
  type
  title
  lang
  companies {
    viewerIsFollowing
    id
    name
    pageUrl
  }
  tags {
    viewerIsFollowing
    id
    name
    pageUrl
  }
  ...PublishingDetails
  ...Reactions
}

fragment ContentMetadata on Content {
  __isContent: __typename
  type
  title
  lang
  pageUrl
  alternatePageUrls: translations {
    __typename
    pageUrl
    lang
  }
  imgUrl
  description
  ... on Video {
    liveTime
    videoUrl
  }
  ... on Webcast {
    liveTime
    videoUrl
  }
}

fragment ContentPageContentQuery_13QmVO on Query {
  content(slug: $contentSlug, type: $type) {
    __typename
    id
    type
    title
    isPremium
    lang
    htmlBody
    summary
    companies {
      forum {
        latestPosts {
          ...ForumPosts
        }
      }
      name
      id
      viewerIsFollowing
      pageUrl
      defaultInstrument {
        isin
        id
        marketOpen
        marketClose
        marketplace {
          region
        }
        returns {
          total
        }
      }
    }
    tags {
      viewerIsFollowing
      id
      name
      pageUrl
    }
    createdAt
    ... on Video {
      liveTime
    }
    ... on Webcast {
      liveTime
    }
    slug
    ... on CompanyReport {
      reportUrl
    }
    ... on ThirdPartyCompanyReport {
      reportUrl
    }
    ... on StockExchangeRelease {
      reportUrl
    }
    ...ContentBasicInfo
    ...ContentMetadata
    ...PriceAndRecommendation_Content
    ...CompanyDetails_Content
    ...ReportLink_Content
    ...KeyFigures_Content
  }
  ...TrendingContent_1jQ2Cn
}

fragment ForumPosts on ForumPost {
  text
  likesCount
  url
  author
  postedAt
  authorImgUrl
}

fragment KeyFigures_Content on Content {
  __isContent: __typename
  companies {
    defaultInstrument {
      estimateData {
        modelType
        reportingCurrency
      }
      snapshot {
        transaction {
          date
          actualized {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
          estimates {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
        }
      }
      id
    }
    id
  }
}

fragment PriceAndRecommendation_Content on Content {
  __isContent: __typename
  createdAt
  companies {
    name
    pageUrl
    defaultInstrument {
      priceData {
        tradeCurrency
      }
      snapshot {
        priceData {
          date
          lastPrice
          tradeCurrency
        }
        transaction {
          date
          recommendation
          targetPrice
        }
        prevTransaction {
          recommendation
        }
      }
      id
    }
    id
  }
}

fragment PublishingDetails on Content {
  __isContent: __typename
  createdAt
  publishers {
    name
    imgUrl
  }
  authors {
    __typename
    id
    name
    slug
    imgUrl
    jobTitle
  }
  ... on Video {
    liveTime
  }
  ... on Webcast {
    liveTime
  }
}

fragment Reactions on Content {
  __isContent: __typename
  id
  reactionGroups {
    reactionType
    reactionsCount
    viewerReacted
  }
}

fragment ReportLink_Content on Content {
  __isContent: __typename
  type
  isPremium
  ... on CompanyReport {
    reportUrl
  }
  ... on ThirdPartyCompanyReport {
    reportUrl
  }
  ... on StockExchangeRelease {
    reportUrl
  }
}

fragment TrendingContent_1jQ2Cn on Query {
  trendingContent(type: ARTICLE) {
    __typename
    id
    title
    lang
    pageUrl
    createdAt
    type
    imgUrl
    companies {
      squareLogoUrl
      name
      id
    }
    authors {
      __typename
      imgUrl
      id
    }
    publishers {
      imgUrl
    }
  }
}


alison-trial-data-presented-at-esmo-gynaecological-cancers-demonstrate-tumor-directed-immune-responses-in-the-majority-of-patients-treated-with-vididencel

__typename

title

isPremium

lang

htmlBody

summary

companies

createdAt

publishers

authors

reactionGroups

pageUrl

translations

imgUrl

description

Mendus develops cancer immunotherapies with a focus on the prevention of tumor recurrence, the leading cause of cancer-related deaths globally. Indications include acute myeloid leukemia, ovarian cancer and soft tissue sarcomas. The company previously went by the name Immunicum and was renamed Mendus following the merger with the Dutch private company DCprime in 2021. Mendus today has its headquarters in Stockholm and its operational activities in Leiden, The Netherlands.

MFN – 5 May 25              Mendus AB (publ): Mendus strengthens late-stage clinical developmen...    Mendus AB ('Mendus' publ; IMMU. ST), a biopharmaceutical company focused on immunotherapies targeting tumor recurrence, today announced the appointment of Tariq Mughal, MD FRCP FRCPath, as Chief Me...                             Kovan tason rekry CMO:ksi Osake +22%

Inderes lopettaa Menduksen seurannan, koska yhtiö on päättänyt analyysisopimuksen. Mendus keskittyy AML-hoitoihin ja tähtää Phase III -vaiheeseen vuoteen 2025 mennessä. Ensimmäinen kaupallistaminen odotetaan vuonna 2029. Suurimmat riskit liittyvät rahoituksen varmistamiseen ja kliinisiin tuloksiin.                   Inderes              Mendus: We are discontinuing coverage - Inderes    We are discontinuing our coverage of Mendus as the company has terminated the equity research agreement. Consequently, we will no longer be giving a target price (was SEK 14) or a recommendation (was Accumulate) for the stock.

Mendus aloitti ilixadencelin uuden kliinisen tutkimuksen suunnittelun pehmytkudossarkoomaa vastaan ja eteni CADENCE-tutkimuksen potilashankinnassa. Kulusäästöjen ansiosta rahavaranto ulottuu nyt Q4’25 asti (aiemmin Q3’25). Alla on Antin näpyttelemä tuore yhtiöraportti Menduksesta.                    Inderes              Mendus Q3'24: Building basis for a pivotal trial - Inderes    In Q3, Mendus reported bringing ilixadencel back into clinical development, opening research centers for the CADENCE trial and progressing in building Phase III readiness.                             In Q3, Mendus reported bringing ilixadencel back into clinical development, opening research centers for the CADENCE trial and progressing in building Phase III readiness. Operating expenses for the quarter came in below our expectations due to implemented cost savings that should continue in the coming months. As a result, the company’s cash runway has been extended into Q4’25 (was Q3’25). We reiterate our target price of SEK 14 and lower our recommendation to Accumulate (was Buy) due to the stock price appreciation relative to our DCF model and Nordic immuno-oncology peers.

Pareto antanut ostosuosituksen tavoitehinnalla 14 kruunua:                  Affärsvärlden              Mendus stiger efter köp från Pareto | Affärsvärlden                              Kurssi +26,88%

Tässä on Antin yhtiöraportti Menduksen Q2:n jälkeen.  Mendukselle Q2/24 merkitsi ratkaisevan CADENCE-tutkimuksen alkua akuutissa myelooisessa leukemiassa (AML). Yhtiö ilmoitti myös suunnitelmista käynnistää uudelleen ilixadencelin kliininen kehitys pehmytkudossarkoomissa (STS). Samanaikaisesti Mendus valmistautuu ratkaisevaan AML-tutkimukseen vuoden 2025 jälkipuoliskolla. Näitä keskeisiä kehityskulkuja tukee turvattu rahoitus Q3/25 asti. Sisällytämme STS-indikaation arvioihimme ja tarkistamme T&K-kustannusarvioitamme ylöspäin tuleville vuosille. Toistamme suosituksemme (Osta) sekä tavoitehintamme 14 SEK, sillä sekä DCF-mallimme että vertailuarvostuksemme viittaavat osakkeen nousupotentiaaliin.  https://www.inderes.fi/research/mendus-q224-ilixadencel-to-return-to-the-clinical-arena

Mendus julkaisi toisen vuosineljänneksen raporttinsa perjantaina 23.8. Toimitusjohtaja Erik Manting tiivistää Antin haastattelussa, mitä tapahtui toisella neljänneksellä sekä kertoo CADENCE-tutkimuksen keskeiset saavutukset sekä kertoo uudesta Ilixadencel-lääkkeen tutkimuksesta.                   Inderes              Mendus Q2´24: The CADENCE trial has started - Inderes    Time: 23.08.2024 klo 15.42 Mendus released their Q2 report today 23/8 and in this interview, you can listen to CEO Erik Manting summarize the second quarter. What has happened during Q2, main milestones in CADENCE and the new communicated trial with...                             Aiheet: 00:00 Start  00:14 What has happened during Q2  04:58 The CADENCE trial  08:04 Main milestones in CADENCE  09:36 Immune activation in AML patients - What have you learned?  12:19 New trial with Ilixadencel  15:16 Timeline for the trial  15:54 Building readiness in AML

Mendus

Press Release Stockholm, Sweden, June 20, 2024Mendus AB (“Mendus” publ; IMMU.ST), a biopharmaceutical company focused on immunotherapies targeting tumor recurrence, today announces that updated...

<div class="mfn-body">Press Release &nbsp; Stockholm, Sweden, June 20, 2024Mendus AB (“Mendus” publ; IMMU.ST), a biopharmaceutical company focused on immunotherapies targeting tumor recurrence, today announces that updated clinical data from the ALISON clinical trial with its lead product vididencel in ovarian cancer will be presented at the ESMO Gynaecological Cancers Annual Congress, being held from June 20-22, 2024 in Florence, Italy. The trial reached its primary objective of inducing tumor-directed immune responses in at least 10 patients treated with vididencel. Ovarian cancer is the deadliest gynaecological cancer, mainly due to its high recurrence rate. Improving disease free and overall survival in advanced high grade serous ovarian carcinoma (HGSC) after primary treatment remains challenging. The Phase 1 ALISON trial explores the potential of vididencel to induce clinically relevant immune responses in ovarian cancer. The trial is fully enrolled (17 participants) and all participants have completed the vididencel treatment phase per April 2024. Vididencel-induced immune responses against tumor antigens that are regularly upregulated in HGSC were observed in 10 out of 15 patients evaluated so far, with 3 patients not reaching a vaccine induced response (VIR) due to high baseline responses. Vididencel treatment only gave mild adverse reactions, predominantly at the site of injection. The observed immune responses following vididencel treatment may provide the basis for an effective anti-tumor response. At week 22, 10 patients had stable disease and 7 patients had imaging-confirmed recurrence. To further evaluate clinical benefit, long-term follow-up of patients is ongoing.Mendus anticipates to report the primary read-out of the ALISON trial based on immune response evaluation of all treated patients in 2024Q4.Please see below for abstract details:Abstract Number:&nbsp; 50P (poster presentation)Abstract Title: Vididencel, a cell-based cancer vaccine, induces tumor-directed immune responses in high-grade serous ovarian carcinoma patientsAuthors: A. Vledder, H. van Zeeburg, K. Brummel, A.L. Eerkens, N. van Rooij, A. Plat, J. Rovers, M. de Bruyn, H. NijmanSession Date &amp; Time: Thursday, 20 June 2024 between 12:30 – 13:30 CESTAfter presentation, the poster will be made available on <a rel="noopener" href="https://mendus-uploads-prod.s3.amazonaws.com/uploads/2024/06/ESMO-gyn2024ALISON.pdf">the Mendus website</a>.</div><div class="mfn-footer mfn-contacts mfn-17d81f918f4c">For more information, please contact:Erik Manting Chief Executive Officer E-mail: <a rel="noopener" href="mailto:ir@mendus.com">ir@mendus.com</a></div><div class="mfn-footer mfn-about mfn-868be8723f72">About Mendus AB (publ)Mendus is dedicated to changing the course of cancer treatment by addressing tumor recurrence and improving survival outcomes for cancer patients, while preserving quality of life. We are leveraging our unparalleled expertise in allogeneic dendritic cell biology to develop an advanced clinical pipeline of novel, off-the-shelf, cell-based immunotherapies which combine clinical efficacy with a benign safety profile. Based in Sweden and The Netherlands, Mendus is publicly traded on the Nasdaq Stockholm under the ticker IMMU.ST.&nbsp;<a rel="noopener" href="https://www.mendus.com/">https://www.mendus.com/</a></div><div class="mfn-footer mfn-attachment mfn-attachment-general">Attachments <a rel="noopener" href="https://storage.mfn.se/10d8188e-1941-421c-a6ff-4b138357dc25/240620-esmo-go-abstract-eng.pdf" class="mfn-primary">240620 ESMO GO Abstract ENG</a></div>

ALISON trial data presented at ESMO Gynaecological Cancers demonstrate tumor-directed immune responses in the majority of patients treated with vididencel