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Analyst Comment

Curasight advances Phase 2 uTRACE® prostate cancer trial

By Philip CoombesEquity Research Analyst
Curasight

Summary

  • Curasight has announced that all nine clinical sites in Germany, Sweden, and Denmark are now recruiting for Part 2 of its Phase 2 uTRACE® trial in prostate cancer, with recruitment expected to complete in H1 2026.
  • The trial aims to validate uTRACE® as a non-invasive imaging tool for prostate cancer diagnosis and risk assessment, under a collaboration with Curium Inc., which could yield up to USD 70 million in milestone payments and double-digit royalties for Curasight.
  • Curasight plans to initiate a Phase 1 study of uTREAT® in brain cancer in Q4 2025, as part of its strategy to combine diagnostic and therapeutic radiopharmaceuticals.
  • HC Andersen Capital receives payment from Curasight for a digitalIR/corporate visibility subscription agreement.

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This morning, Curasight announced that all nine clinical sites across Germany, Sweden, and Denmark are now recruiting patients in Part 2 of its ongoing Phase 2 uTRACE® trial in prostate cancer, following completion of Part 1 earlier this year. Recruitment is expected to be finalized in H1 2026, marking solid operational progress under the company’s collaboration with Curium Inc., a global leader in nuclear medicine.

The study aims to validate uTRACE® as a non-invasive imaging tool for improved diagnosis and risk assessment in prostate cancer patients under active surveillance. Under its agreement with Curium, Curasight is eligible for up to USD 70 million in milestone payments and double-digit royalties upon commercialization. Alongside this trial, Curasight also expects to initiate a Phase 1 study of uTREAT® in brain cancer later this quarter (Q4 2025), advancing its broader theranostic strategy combining diagnostic and therapeutic radiopharmaceuticals.

Disclaimer: HC Andersen Capital receives payment from Curasight for a digitalIR/corporate visibility subscription agreement. / Philip Coombes 08:33 29/10/2025

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Curasight is a Danish biotech company focusing on developing and improving the detection and treatment of cancer in a more gentle and efficient way. The company has two pipeline products that both use radionuclide (nuclear medicine) to facilitate better diagnosis and treatment of various cancer types; uTRACE use the so-called uPAR as a biomarker to diagnose the aggressiveness of cancer, and uTREAT use the uPAR as a attachment to treat the cancer. Based on good phase 2 data that has already been collected or will be in the first half of 2022, Curasight is expected to prepare phase 3 for uTRACE later in 2022 and 2023 for the following four cancer types: prostate, brain, neuroendocrine, and head and neck cancer.

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