contentSlug

type

ContentSlug_ContentQuery

slug

ContentPageContentQuery

content

trendingContent

query ContentSlug_ContentQuery(
  $contentSlug: String!
  $type: [ContentType!]
) {
  ...ContentPageContentQuery_13QmVO
}

fragment CompanyDetails_Content on Content {
  __isContent: __typename
  companies {
    name
    description
    pageUrl
    id
  }
}

fragment ContentBasicInfo on Content {
  __isContent: __typename
  id
  type
  title
  lang
  companies {
    viewerIsFollowing
    id
    name
    pageUrl
  }
  tags {
    viewerIsFollowing
    id
    name
    pageUrl
  }
  ...PublishingDetails
  ...Reactions
}

fragment ContentMetadata on Content {
  __isContent: __typename
  type
  title
  lang
  pageUrl
  alternatePageUrls: translations {
    __typename
    pageUrl
    lang
  }
  imgUrl
  description
  ... on Video {
    liveTime
    videoUrl
  }
  ... on Webcast {
    liveTime
    videoUrl
  }
}

fragment ContentPageContentQuery_13QmVO on Query {
  content(slug: $contentSlug, type: $type) {
    __typename
    id
    type
    title
    isPremium
    lang
    htmlBody
    summary
    companies {
      forum {
        latestPosts {
          ...ForumPosts
        }
      }
      name
      id
      viewerIsFollowing
      pageUrl
      defaultInstrument {
        isin
        id
        marketOpen
        marketClose
        marketplace {
          region
        }
        returns {
          total
        }
      }
    }
    tags {
      viewerIsFollowing
      id
      name
      pageUrl
    }
    createdAt
    ... on Video {
      liveTime
    }
    ... on Webcast {
      liveTime
    }
    slug
    ... on CompanyReport {
      reportUrl
    }
    ... on ThirdPartyCompanyReport {
      reportUrl
    }
    ... on StockExchangeRelease {
      reportUrl
    }
    ...ContentBasicInfo
    ...ContentMetadata
    ...PriceAndRecommendation_Content
    ...CompanyDetails_Content
    ...ReportLink_Content
    ...KeyFigures_Content
  }
  ...TrendingContent_1jQ2Cn
}

fragment ForumPosts on ForumPost {
  text
  likesCount
  url
  author
  postedAt
  authorImgUrl
}

fragment KeyFigures_Content on Content {
  __isContent: __typename
  companies {
    defaultInstrument {
      estimateData {
        modelType
        reportingCurrency
      }
      snapshot {
        transaction {
          date
          actualized {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
          estimates {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
        }
      }
      id
    }
    id
  }
}

fragment PriceAndRecommendation_Content on Content {
  __isContent: __typename
  createdAt
  companies {
    name
    pageUrl
    defaultInstrument {
      priceData {
        tradeCurrency
      }
      snapshot {
        priceData {
          date
          lastPrice
          tradeCurrency
        }
        transaction {
          date
          recommendation
          targetPrice
        }
        prevTransaction {
          recommendation
        }
      }
      id
    }
    id
  }
}

fragment PublishingDetails on Content {
  __isContent: __typename
  createdAt
  publishers {
    name
    imgUrl
  }
  authors {
    __typename
    id
    name
    slug
    imgUrl
    jobTitle
  }
  ... on Video {
    liveTime
  }
  ... on Webcast {
    liveTime
  }
}

fragment Reactions on Content {
  __isContent: __typename
  id
  reactionGroups {
    reactionType
    reactionsCount
    viewerReacted
  }
}

fragment ReportLink_Content on Content {
  __isContent: __typename
  type
  isPremium
  ... on CompanyReport {
    reportUrl
  }
  ... on ThirdPartyCompanyReport {
    reportUrl
  }
  ... on StockExchangeRelease {
    reportUrl
  }
}

fragment TrendingContent_1jQ2Cn on Query {
  trendingContent(type: ARTICLE) {
    __typename
    id
    title
    lang
    pageUrl
    createdAt
    type
    imgUrl
    companies {
      squareLogoUrl
      name
      id
    }
    authors {
      __typename
      imgUrl
      id
    }
    publishers {
      imgUrl
    }
  }
}


lipum-presents-new-topline-data-supporting-bssls-role-in-rheumatoid-arthritis

__typename

title

isPremium

lang

htmlBody

summary

companies

createdAt

publishers

authors

reactionGroups

pageUrl

translations

imgUrl

description

Lipum is a biopharmaceutical company. The company is in the clinical phase and specializes in the discovery and development of new treatments for chronic inflammatory diseases. The company's drug candidate is based on an antibody intended to be used in treatments to block a specific molecule in the immune system. The drug candidate is in the clinical phase with preclinical data for rheumatism. The company is also evaluating other inflammatory diseases. Lipum has its operations in Umeå.

Lipum

Lipum AB (publ) today announced topline results from collaborative studies with Senior Associate Professor Alf Kastbom and team at Linköping University that further support the role of bile ...

<div class="mfn-preamble"><p><strong>Lipum AB (publ) today announced topline results from collaborative studies with Senior Associate Professor Alf Kastbom and team at Linköping University that further support the role of bile salt-stimulated lipase (BSSL) in rheumatoid arthritis (RA).</strong></p></div><div class="mfn-body"><p>The data from 263 subjects show that patients with recent-onset RA (n=174) have significantly higher BSSL levels in the circulation compared to healthy controls (n=89), and that BSSL levels correlate with disease activity, measured by the 28-joint disease activity score (DAS28) and inflammation measured by CRP and ESR. The results strengthen the rationale for Lipum’s lead candidate, SOL-116, a first-in-class humanized antibody designed to neutralize BSSL and reduce chronic inflammation in RA.</p><p><em>"These results confirm our long-standing hypothesis that BSSL is not only present in blood samples from patients with inflammatory disorders but is also linked to disease activity. This adds valuable support to our ongoing clinical development of SOL-116",</em>&nbsp;said Susanne Lindquist, CSO of Lipum.&nbsp;</p><p>The results form part of Lipum’s expanding clinical and translational research program and will be used to strengthen the clinical development of SOL-116. In parallel, BSSL analyses will be included across all patients in the clinical trial program going forward to support stratification and provide further insights into its role as a biomarker.</p><p><em>"Our upcoming phase II study will give us the opportunity to further explore the therapeutic potential of targeting BSSL in patients with active RA, while also collecting valuable data on BSSL levels in chronic inflammatory diseases”, </em>said Ola Sandborgh, CEO of Lipum<em>.</em></p></div><div class="mfn-footer mfn-contacts mfn-3e7c58a90e0f"><p><strong class="mfn-heading-1">Contacts</strong><br>Ola Sandborgh, CEO<br><a rel="noopener" href="mailto:ola.sandborgh@lipum.se">ola.sandborgh@lipum.se</a><br>+46 72 218 80 21<br>Web: <a rel="noopener" href="http://www.lipum.se">www.lipum.se</a></p></div><div class="mfn-footer mfn-about mfn-6ab0b4f78e1d"><p><strong class="mfn-heading-1">About Us</strong><br>Lipum AB (publ) is a clinical stage biopharmaceutical company specialized in discovery and development of a novel treatment for chronic inflammatory diseases. The lead candidate SOL-116 is a humanized antibody designed to provide efficacious therapy by blocking a previously overlooked target molecule of the immune system (BSSL). SOL-116 is in clinical phase with a successfully completed Phase 1 study. Together with strong preclinical data, we have a solid foundation for continued development in the treatment of rheumatoid arthritis. Lipum also explores other inflammatory diseases with a high unmet medical need. The company is based in Umeå, an excellent life science cluster in Sweden. Lipum’s unique approach has attracted international attention, including a major European Commission Horizon 2020 grant. The company's share (LIPUM) is traded on the Nasdaq First North Growth Market. Certified Adviser is&nbsp;G&amp;W Fondkommission.</p></div><div class="mfn-footer mfn-attachment mfn-attachment-general"><p><strong class="mfn-heading-1">Attachments</strong><br><a rel="noopener" href="https://storage.mfn.se/2ffc2b3b-f136-497b-99ac-3125c6a5061a/lipum-presents-new-topline-data-supporting-bssls-role-in-rheumatoid-arthritis.pdf" class="mfn-generated mfn-primary">Lipum presents new topline data supporting BSSL’s role in rheumatoid arthritis</a></p></div>

Lipum presents new topline data supporting BSSL’s role in rheumatoid arthritis