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Regulatory press release

Nykode Therapeutics - Mandatory notification of acquisition of shares by primary insider

Nykode Therapeutics
Oslo, Norway, October 10, 2025 - Primary insider Michael Engsig, Chief Executive
Officer of Nykode Therapeutics ASA, has today acquired 55,944 shares in Nykode
Therapeutics ASA at a price of NOK 1.79 per share. Following the transaction,
Michael Engsig holds 71,794 shares in Nykode Therapeutics ASA.

Please see further details in the attached document.
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